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Cure America of Anosognosia

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Agenesis of the Corpus Callosum

Contributor: Brooke Herd- Azusa Pacific University, Department of Clinical Psychology, Psy.D. Student​Agenesis of the corpus callosum (AgCC) is a rare congenital condition resulting from the complete absence (cAgCC) or hypogenesis (partial absence; pAgCC) of the corpus callosum [1-2]. The corpus callosum is the main commissure connecting the two cerebral hemispheres, and is composed of about 200 million axonal connections [3]. A typically developing corpus callosum serves to pr […] …

Inhibitory control in children with ADHD

Contributor: Erin Kaseda, Brigham Young University, Neuroscience undergraduate & ANST MemberOverview:  It is estimated that between 5-10% of children and adolescents in the United States have been diagnosed with attention-deficit/hyperactivity disorder (ADHD) [1]. Developmentally appropriate self-regulation allows for social flexibility and goal-oriented motivation; traits often diminished in children with ADHD [2].  Pediatric ADHD populations typically experi […] …

Assessing Performance and Symptom Validity during Neuropsychological Evaluation

Contributor: Zach Greth, BS –University of North Carolina at Charlotte Topic Overview Concerns over malingering and invalid symptom reporting continue to escalate within clinical and forensic settings. Recent rates suggest some 19-68% of U.S. Social Security Administration (SSA) disability claims have been reported to include elements of compromised effort and feigning during clinical evaluation [6]. This can be problematic if claimants are erroneously compensate […] …

Cannabinoid Legalization Unintentionally Impacts Pediatric Neurodevelopment

Contributor: Amelia Howard, M.S.- Azusa Pacific University, Department of Clinical Psychology, Psy.D. Program (Doctoral Student)Overview:Cannabinoids or delta-9-tetrahydrocannabinol (Δ9-THC) is commonly referred to as Marijuana [1]. There are over 180 million users worldwide and 22.2 million users in the US [1-2]. A comprehensive review of published studies, case series, and case reports revealed that 3,582 children, age 12 years or less, unintentionally ingested cann […] …

Neuroprogression in Bipolar Disorder

Contributor: Robmarie Lopez-Soto, M.S., PhD Candidate in Clinical Psychology, Ponce Health Sciences UniversityOverview:Bipolar Disorder (BD) is a neuropsychiatric illness that is the sixth leading cause of disability worldwide [1]. BD is characterized by alternating manic and depressive mood episodes, with interspersed periods of euthymia that vary in length depending on biochemical, clinical and psychosocial factors implicated in age of illness onset, mood episode frequency and […] …

Anticholinergic Medications and Cognitive Functioning

Contributor: Thomas R. Valentine, M.A., PhD Candidate in Clinical Psychology, The Ohio State University Overview:Anticholinergic medications are a diverse class of drugs that block the binding of the neurotransmitter acetylcholine to receptors in the central and peripheral nervous system [1]. These agents treat a variety of physical and mental health conditions, including seasonal allergies, gastrointestinal distress, overactive bladder, insomnia, anxiety, and depression[2]. Ant […] …

Noninvasive Assessment of Language Laterality in Pre-Surgical Epilepsy Patients

Contributor: Briana Brukilacchio, M.Ed.,  The University of Texas at Austin, PhD Program in School Psychology​Topic OverviewAn estimated 15% of all patients with focal epilepsy syndromes do not experience substantial relief when treated with anticonvulsant medications alone [1]. For these patients with intractable epilepsy, surgical intervention is often indicated [2]. In order to maximize postoperative benefits and minimize the risk of associated impairments, such pa […] …

The Role of Biomarkers in Diagnosing Alzheimer’s Disease

Contributor: Yosefa Allegra Ehrlich, M.Phil., Ph.D. Candidate in Clinical Psychology, Queens College, City University of New York (CUNY) Overview:The use of biomarkers in diagnosing Alzheimer’s disease (AD) in vivo is gaining popularity. Biomarkers refer to measureable characteristics that indicate the presence of biologic and/or pathologic processes (1). This shift is based on an expanding body of research indicating that in vivo methods […] …

Amyotrophic Lateral Sclerosis with Frontotemporal Dementia

Contributor: Daniella Ladowski, M.Sc., University of Western Ontario (Doctoral Candidate) Topic overview:Amyotrophic Lateral Sclerosis (ALS), also referred to as motor neuron disease, is a progressive disease affecting both upper and lower motor neurons. According to the El Escorial criteria [1] and its revisions [2-5], diagnosis is largely based on clinical and electrophysiological evidence of motor neuron dysfunction to the exclusion of other motor disorders. However, ALS may […] …